The WorldFish mission is to strengthen livelihoods and enhance food and nutrition security by improving fisheries and aquaculture. We pursue this through research partnerships focused on helping those who stand to benefit the most--poor producers and consumers, women and children This strategy details the ambitious impact targets we have embraced, which are aligned with the UN Sustainable Development Goals, and charts our course to achieve them. We focus our research on the three interlinked challenges of sustainable aquaculture, resilient small-scale fisheries, and enhancing the contributions of fish to nutrition of the poor in the places where we can make the most difference. These challenges will only be met by partnering with the communities, research innovators, entrepreneurs and investors who give fisheries and aquaculture their dynamism and promise.